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ART's Unique Bioresorbable Stent
ART’s bioresorbable stent provides the requisite initial mechanical scaffolding to resist recoil; then, as it dismantles over time in a controlled fashion because of its polylactic acid makeup, the possibility of natural remodeling returns to the artery.

Lactic Acid Polymer
ART is developing one of the world’s first bioresorbable stents made from a biocompatible lactic acid polymer enabling the ART stent to support an artery triggering only minimal local tissue response causing restenosis.
“The most critical aspect of the degradation process for a bioresorbable stent is the dismantling-over-time factor, and not total disappearance”.

Gradual Dismantling Is Key
ART’s proprietary stent provides the requisite initial acute mechanical scaffolding to resist severe recoil, but as it dismantles due to bioresorbability, the possibility of arterial remodeling returns to the artery. ART’s stent technology not only overcomes many disadvantages of metal stents, but is biocompatible and will disappear over time as it bioresorbs. In addition, ART’s polymer can be shown to be safe and trigger a minimal inflammatory response. The most important portion of the degradation process is the dismantling event, not total disappearance. Dismantling or loss of physical integrity is the process that allows the arterial remodeling mechanism to proceed. “The ART platform provides the added benefit of total disappearance over time (one to two years, or less, if needed) in a safe manner. Arterial walls remodel, naturally, adjusting their size for optimal blood flow. Meanwhile, the stent gradually dismantles into lactic acid molecules, which are carried away via natural biochemical pathways,” says Dr. Michel Vert, a scientific advisor to ART who has 30 years of experience working with bioresorbable polymers. “ART’s stent is comprised entirely of its specific lactic acid polymer, making the stent non-inflammatory, biocompatible and hemocompatible, as well as mechanically strong and bioresorbable,” adds Dr. Vert, a former Director of the research unit specializing in biopolymers at the Univ. of Montpellier 1 and National Center of Scientific Research headquartered in Paris.